Juniper Publishers: JAK2 and Its Regulators beyond Myeloproliferative ...

Juniper Publishers: JAK2 and Its Regulators beyond Myeloproliferative ...: JUNIPER PUBLISHERS-Journal of Tumor Medicine & Prevention JAK2 and Its Regulators beyond Myeloproliferative Neoplasms Aut...

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Research Article Intrauterine Insemination with Fresh Versus Cryopreserved Spermatazoa in Unexplained Infertility

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Global Journal of Reproductive Medicine    Juniper Publishers Authored by: Sheena Rippentrop* Introduction Infertility affects approximately 14% of couples in the general population and is defined as failure to conceive after 12 months of regular unprotected intercourse. Unexplained infertility accounts for up to 15-30% of the diagnoses in couples [1,2]. The diagnosis of unexplained infertility is one of exclusion and can only be made after investigating the common causes of infertility using standard testing including evaluation for male and female infertility [1]. This evaluation typically involves assessment of ovulation, ovarian reserve, fallopian tube patency, uterine and cervical factors, along with semen analysis. In couples with infertility, previous studies have shown that ovulation induction with intrauterine insemination (IUI) provides a less invasive and more cost-effective treatment option when compared to in-vitro fertilization in couples with ...
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Ruptured Rudimentary Horn Pregnancy in a Multiparous Patient: A Case Report and Literature Review

Global Journal of Reproductive Medicine    Juniper Publishers Authored by:  Sarwat Khan* Case Report We present a case report of 31 yrs old Gravida 4 para 2+1 patient with two previous term vaginal deliveries. She presented with a rupture of undiagnosed rudimentary horn of uterus at 18 weeks. Laparotomy was performed and rudimentary horn was excised with good recovery postoperatively. The need for high index of suspicion and early diagnosis using ultrasonography is emphasised. Conclusion: Pregnancy in a rudimentary horn carries grave risk to the mother. There is need for increase awareness of this rare condition and to have a high index of suspicion at time of booking. Go to Introduction Mullerian duct anomalies occur during embryonic development due to defective fusion, canalization or absorption of the median septum of the Mullerian ducts in the female reproductive system [ 1 ]. The prevalence of mullerian duct anomalies in the general female popu...
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Sperm-Oviduct Interaction Factors that Compromise Fertility of Frozen Stallion Semen

Global Journal of Reproductive Medicine   Juniper Publishers Abstract The cryopreservation procedure changes the integrity and functionality of sperm, affecting their longevity and the ability to fertilize the oocyte. Moreover, some of those changes could be alter the physiologic interactions between the sperm and the oviductal epithelial cells prior to fertilization, placing further limitations and challenges on frozen-thawed stallion sperm. For fertilization to occur, a sperm subpopulation should be survive in uterine environment and be transported to oviduct, the tubular epithelium that regulate the sperm capacitation process in tuning with the ovulation and later oocyte fecundation. Factors affecting sperm-oviduct interactions in equine and findings in other mammals suggest that this interaction is highly conserved. However, there are differences between species and this interaction may assist to explain the idiopathic infertility associated with t...
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