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Showing posts from July, 2019

The Mooncup: A Tool to Measure Menstrual Bleeding Loss Volume

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Global Journal of Reproductive Medicine    Juniper Publishers Abstract Background:  The mooncup is not a tool habitually used for quantifying the volume of menstrual blood loss. Objective:  The aims of the study were to explore mooncup management by Spanish women and estimate the volume of menstrual blood loss. Method:  This is a comparative observational study involving 94 healthy women who participated voluntarily following a mass invitation on Face book. This is an accidental, non-probability sampling technique. The participants completed an online questionnaire drafted using the following program: https://docs.google.com/spreadsheets/u/0/, which included socio-demographic and mooncup use factors, with the aim of estimating menstrual volume. Depending on individual hygiene habits the cup was emptied when full, half-full or only stained. Result:  Overall, a mean figure of 3,25 cups/woman/day were emptied (SD 1.77, CI 95%, 2.88-3.61). T...

Participating Ectopic Receptor Biology and Etiologic and Pathogenic Stromal Sub-Component Systems in Prostatic Carcinogenesis

Global Journal of Reproductive Medicine    Juniper Publishers Abstract Substantial correlation exists between ectopic FGFR1 localization in prostatic glandular epithelial cells and the initiation or more specifically the promotion of development of prostatic adenocarcinoma in mouse models indicates the susceptibility of these cells to aberrant FGFR dysfunction. Regulatory dysfunction of the FGFR pathways is clearly carcinogenic and implicates disordered pathway dysfunction within the system promiscuity with such pathways as ERK, MAPK, RAS, and various subsequent downstream effectors in carcinogenesis ofthe prostate. miR-512- 3p appears associated with the mitogen-activated protein kinase signaling pathway and also cell adhesion, cell proliferation, cell cycling and apoptosis [ 1 ]. Homeostatic disturbance The homeostatic compartmentalization of prostatic glandular epithelium as luminal and basal cell components and also the neuroendocrine cellular...

Readiness to Provide Reproductive Health Services to Young People

Global Journal of Reproductive Medicine    Juniper Publishers Abstract Providing reproductive health services to young people has shown to be a difficult task. Current research suggests training and equipping health care workers with the right resources and equipment would significantly improve the provision of reproductive services [ 1 ]. Research conducted in differing countries tend to have the same outcome. Young people are a special population and providing services in a sensitive area, like reproduction and gynecology must be given focus and attention, in order to ensure quality care is provided [ 1 ]. Discussion Young people have many different reproductive health needs. An estimated 15 million women between the ages 15 to 19 give birth each year [ 2 ]. That same group of women have the highest rate of STI's worldwide with growing numbers in developing countries [ 2 ]. Young men and women alike are ...

Clinical Dilemmas and Risks of Misdiagnosis and Mismanagement Associated with Endogenous Caesarean Scar Pregnancy: A Case Series and Literature Review

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Global Journal of Reproductive Medicine    Juniper Publishers Abstract A caesarean scar pregnancy (CSP) is a pregnancy that implants into the myometrium at the site of a previous uterine incision. In this paper, we present three cases of women affected by caesarean scar implantations. Each case presented differently and was managed in separate ways. We describe their differing presentations and care as well as reflecting on how such women may be better cared for. Endogenic CSPs grow into the uterine cavity and can easily be mistaken for a normal pregnancy implantation. Differentiation can often only be seen at early gestations. All women with a previous uterine scar should potentially be offered early trans-vaginal ultrasound to correctly diagnose the implantation site. However, in many women, the diagnosis is not suspected until a complication arises. We advocate for there to be a higher index of suspicion for CSPs during early pregnancy ultrasound ...

Sperm-Oviduct Interaction Factors that Compromise Fertility of Frozen Stallion Semen

Global Journal of Reproductive Medicine   Juniper Publishers Abstract The cryopreservation procedure changes the integrity and functionality of sperm, affecting their longevity and the ability to fertilize the oocyte. Moreover, some of those changes could be alter the physiologic interactions between the sperm and the oviductal epithelial cells prior to fertilization, placing further limitations and challenges on frozen-thawed stallion sperm. For fertilization to occur, a sperm subpopulation should be survive in uterine environment and be transported to oviduct, the tubular epithelium that regulate the sperm capacitation process in tuning with the ovulation and later oocyte fecundation. Factors affecting sperm-oviduct interactions in equine and findings in other mammals suggest that this interaction is highly conserved. However, there are differences between species and this interaction may assist to explain the idiopathic infertility associated with t...