GHR106 Monoclonal Antibody is Bioequivalent to GnRH Peptide Analogs-Juniper Publishers-Global Journal Of Reproductive Medicine

JUNIPER PUBLISHERS-GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE

GHR106 Monoclonal Antibody is Bioequivalent to GnRH Peptide Analogs

Authored by Gregory Lee*

GnRH (gonadotropin releasing hormone) is a decapeptide hormone and was discovered initially to react with GnRH receptor in the anterior pituitary. This hormone serves to stimulate the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) for the differentiation and maturations of reproductive functions. Due to the relative short half-life of GnRH (in min) in circulations, numerous peptide analogs were made available to increase the half-life of these GnRH analogs to hours. Due to structural modifications, they were classified into either agonists or antagonists, depending on their respective biological actions.

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