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Cylinders and Assemblage- Sertoli-Leydig Cell Tumour -Ovary

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  GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE -JUNIPER PUBLISHERS Sertoli-Leydig cell tumour is an exceptionally discerned, ovarian neoplasm composed of sex cord or Sertoli cells admixed with stromal component expounded by Leydig cells. Sertoli-Leydig cell tumour may occur in association with DICER1 syndrome or emerge as a sporadic phenomenon. Sertoli-Leydig cell tumour manifests as well differentiated, moderately differentiated or intermediate grade and poorly differentiated neoplasms. Additionally, categories such as Sertoli-Leydig cell tumour with heterologous elements or retiform variant of Sertoli-Leydig cell tumour may be expounded. Majority of paediatric Sertoli- Leydig cell tumours are moderately differentiated or poorly differentiated, concur with DICER1 syndrome and frequently display heterologous elements or retiform tumour configuration. Histological categorization of neoplasms with enhanced tumour grade appears challenging [1,2]. Well differentiated tumefaction exhibits di...

COVID-19 Vaccination in Pregnancy

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  GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE -JUNIPER PUBLISHERS Abstract COVID-19 pandemic has affected human lives globally. The most important measure to control this pandemic is vaccination and to follow public health measures like wearing facemasks, maintaining social distancing, and hygiene. Over the last one-year, numerous vaccines have been formulated under rigorous regulatory rules globally. During the process of vaccine development, antenatal and breastfeeding women were not included in vaccine research trials, even though they were at increased risk of developing severe COVID-19 infection in comparison to non-pregnant women. There is reassuring data that there are no safety concerns in antenatal patients who received mRNA vaccine in the third trimester and no evidence of increased miscarriage rate if taken at less than 20 weeks of pregnancy. In mRNA vaccine immunized pregnant women, antibodies were found in cord blood. The healthcare staff should provide effective counselli...

Miracle Pregnancy: Management of Poor Responder in In-Vitro Fertilization

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  GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE -JUNIPER PUBLISHERS Abstract Background: : Patient-Oriented Strategy Encompassing IndividualizeD Oocyte Number (POSEIDON) 3 and 4 subgroup is common nowadays. We hereby report a case of successful management of POSEIDON 4 patient, who underwent an individualized GnRH antagonist protocol. Case Presentation: : A 36-year-old woman presented with primary infertility for 10 years. She had undergone multiple cycles of ovulation induction and intrauterine insemination previously. She had previous one IVF failure. Post COVID lockdown, patient was a POSEIDON 4 group patient who underwent second IVF cycle. Three grade 4 oocytes were retrieved after dual trigger. Two 8 celled grade B embryos were transferred on day 3. Patient conceived and had caesarean section at 37 weeks POG, 2.4 kg healthy male baby delivered. Conclusion: : IVF with self-oocyte can be tried along with proper counselling to decrease the psychological and financial burden on the pati...

Acupuncture Treatment for POI Resulted in Successful IVF: A Case Report

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  GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE- JUNIPER PUBLISHERS Abstract This article presents a case report of a primary infertility patient diagnosed with Premature Ovarian Insufficiency (POI), who failed three attempts of IVF and two IUI treatments. After which acupuncture was used as a treatment and produced a successful IVF. The patient, a 36-year-old woman, presented at our clinic with high FSH 35, low AMH <0.1, AFC 4, and primary infertility for more than 1.5 years. She wanted to improve her ovarian reserve, egg quality, and her chances of successful IVF. The patient received 27 acupuncture treatments over the course of 8 months, which resulted in pregnancy. This case suggests that acupuncture is an effective treatment for IVF patients with POI. Keywords:  Premature Ovarian Insufficiency; In Vitro Fertilization; Acupuncture; Low AMH; Infertility Abbreviations:  AFC: Antral Follicle Count; AMH: Anti-Mullerian Hormone; ET: Embryo Transfer; FSH: Follicle-Stimulating ...

Effect of Prolonged GnRH Agonist Therapy Prior to Frozen Embryo Transfer on IVF-ET Outcome in Patients with and without Endometrioma Surgery

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  GLOBAL JOURNAL OF REPRODUCTIVE MEDICINE-JUNIPER PUBLISHERS Abstract Objective : It remains to be clarified whether prolonged Gonadotrophin-Releasing Hormone agonist (GnRHa) administration before frozen embryo transfer to patients with and without endometrioma resection improves reproductive outcome. This study was designed to investigate freeze-all cycles with subsequent prolonged GnRHa administration in patients with and without endometrioma surgery. Method : A total of 164 patients with complaints of infertility and diagnosed with endometrioma were included in this case controlled study. Endometrioma resection was performed in 65 out of 164 women and then Controlled Ovarian Stimulation (COS) was performed (Group 1). Fresh embryos were transferred to 40 of 65 patients who underwent endometrioma surgery. Embryos were vitrified in 25 patients and administered leuprolide acetate 3.75 mg for 3 months. The remaining 99 patients were referred directly to the COS without any surgery fo...