Posts

Showing posts from July, 2022

Let’s Talk and Grow Together: A Bidirectional Communication between Granulosa- and Oocyte Derived Factors in the Ovary

  Abstract Reproduction, one of the most active and appealing area of research for endocrinologists and reproductive biologists since many a years, has several faces that remains to be unmasked in terms of its regulatory aspects. Available information on the regulation of oocyte development and maturational competence are gaping and needs elucidation to achieve utmost quality of eggs, a major area of concern. The notion of the somatic follicular cells providing an appropriate microenvironment for the development of oocyte throughout its journey has been replaced with the current perception of a complex yet regulated cross-talk between the granulosa-and oocyte-derived factors to orchestrate follicle development. Interestingly, actions of FSH and LH are mediated or modulated by these locally produced non-steroidal peptide factors from the follicular layer and the oocyte itself (insulin-like growth factors (IGFs), epidermal growth factor (EGF) family members, TGFβ super family members...

Determinants of Abortion among Youth Seeking Reproductive Health Care in Selected Health Facilities, in Addis Ababa, Ethiopia

  Abstract Background:  Most of the students in higher education institutions are young, aged 19-24, who are often sexually active, and among the most vulnerable and at risk of HIV infection and other sexual and reproductive health problems. Taking this in to account HIV/AIDS and SRH intervention has been taking place in Ambo University. With the expectation that it will help the program manager to improve the intervention, this study was aimed to monitor the intervention of HIV/AIDS and SRH program in the University. Methods:  A qualitative study using in-depth interview and document review were used to collect primary and secondary data, respectively. A total of 13 study participants constituting the university's HIV/AIDS prevention and control office focal person, campus clinic officer, guidance and counseling officer and 10 students from different departments were purposely selected for the in-depth interview. The interviews were audio-taped digitally, transcribed ver...